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Generation of functional ciliated cholangiocytes from human pluripotent stem cells

The derivation of mature functional cholangiocytes from human pluripotent stem cells (hPSCs) provides a model for studying the pathogenesis of cholangiopathies and for developing therapies to treat them. Current differentiation protocols are not efficient and give rise to cholangiocytes that are not...

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Detalles Bibliográficos
Autores principales: Ogawa, Mina, Jiang, Jia-Xin, Xia, Sunny, Yang, Donghe, Ding, Avrilynn, Laselva, Onofrio, Hernandez, Marcela, Cui, Changyi, Higuchi, Yuichiro, Suemizu, Hiroshi, Dorrell, Craig, Grompe, Markus, Bear, Christine E., Ogawa, Shinichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586142/
https://www.ncbi.nlm.nih.gov/pubmed/34764255
http://dx.doi.org/10.1038/s41467-021-26764-0