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Sacubitril Ameliorates Cardiac Fibrosis Through Inhibiting TRPM7 Channel

Heart failure caused by cardiac fibrosis has become a major challenge of public health worldwide. Cardiomyocyte programmed cell death (PCD) and activation of fibroblasts are crucial pathological features, both of which are associated with aberrant Ca(2+) influx. Transient receptor potential cation c...

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Detalles Bibliográficos
Autores principales: Jia, Tian, Wang, Xiaozhi, Tang, Yiqun, Yu, Wenying, Li, Chenhui, Cui, Shufang, Zhu, Juanjuan, Meng, Wei, Wang, Chen, Wang, Quanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586221/
https://www.ncbi.nlm.nih.gov/pubmed/34778271
http://dx.doi.org/10.3389/fcell.2021.760035