Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

Lung diseases, such as cystic fibrosis and COPD, are characterized by mucus obstruction and chronic airway inflammation, but their mechanistic link remains poorly understood. Here, we focus on the function of the mucostatic airway microenvironment on epigenetic reprogramming of airway macrophages (A...

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Detalles Bibliográficos
Autores principales: Hey, Joschka, Paulsen, Michelle, Toth, Reka, Weichenhan, Dieter, Butz, Simone, Schatterny, Jolanthe, Liebers, Reinhard, Lutsik, Pavlo, Plass, Christoph, Mall, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586227/
https://www.ncbi.nlm.nih.gov/pubmed/34764283
http://dx.doi.org/10.1038/s41467-021-26777-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586227/
https://www.ncbi.nlm.nih.gov/pubmed/34764283
http://dx.doi.org/10.1038/s41467-021-26777-9

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