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Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass

O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specific impact of O-GlcNAcylation on mitochondrial morphology and...

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Detalles Bibliográficos
Autores principales: Akinbiyi, Elizabeth O., Abramowitz, Lara K., Bauer, Brianna L., Stoll, Maria S. K., Hoppel, Charles L., Hsiao, Chao-Pin, Hanover, John A., Mears, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586252/
https://www.ncbi.nlm.nih.gov/pubmed/34764359
http://dx.doi.org/10.1038/s41598-021-01512-y