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Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass
O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specific impact of O-GlcNAcylation on mitochondrial morphology and...
Autores principales: | Akinbiyi, Elizabeth O., Abramowitz, Lara K., Bauer, Brianna L., Stoll, Maria S. K., Hoppel, Charles L., Hsiao, Chao-Pin, Hanover, John A., Mears, Jason A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586252/ https://www.ncbi.nlm.nih.gov/pubmed/34764359 http://dx.doi.org/10.1038/s41598-021-01512-y |
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