Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes

An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small cell lung cancers (NSCLC) are deficient in LIMD1, yet this s...

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Detalles Bibliográficos
Autores principales: Davidson, Kathryn, Grevitt, Paul, Contreras-Gerenas, Maria F., Bridge, Katherine S., Hermida, Miguel, Shah, Kunal M., Mardakheh, Faraz K., Stubbs, Mark, Burke, Rosemary, Casado, Pedro, Cutillas, Pedro R., Martin, Sarah A., Sharp, Tyson V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586256/
https://www.ncbi.nlm.nih.gov/pubmed/34764236
http://dx.doi.org/10.1038/s41419-021-04355-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586256/
https://www.ncbi.nlm.nih.gov/pubmed/34764236
http://dx.doi.org/10.1038/s41419-021-04355-7

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