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TERT Alterations Predict Tumor Progression in De Novo High-Grade Meningiomas Following Adjuvant Radiotherapy

BACKGROUND: Adjuvant radiotherapy (RT) is one of the most commonly used treatments for de novo high-grade meningiomas (HGMs) after surgery, but genetic determinants of clinical benefit are poorly characterized. OBJECTIVE: We describe efforts to integrate clinical genomics to discover predictive biom...

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Detalles Bibliográficos
Autores principales: Deng, Jiaojiao, Sun, Shuchen, Chen, Jiawei, Wang, Daijun, Cheng, Haixia, Chen, Hong, Xie, Qing, Hua, Lingyang, Gong, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586415/
https://www.ncbi.nlm.nih.gov/pubmed/34778063
http://dx.doi.org/10.3389/fonc.2021.747592