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Adeno-Associated Viruses (AAV) and Host Immunity – A Race Between the Hare and the Hedgehog

Adeno-associated viruses (AAV) have emerged as the lead vector in clinical trials and form the basis for several approved gene therapies for human diseases, mainly owing to their ability to sustain robust and long-term in vivo transgene expression, their amenability to genetic engineering of cargo a...

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Detalles Bibliográficos
Autores principales: Rapti, Kleopatra, Grimm, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586419/
https://www.ncbi.nlm.nih.gov/pubmed/34777364
http://dx.doi.org/10.3389/fimmu.2021.753467