The TSC Complex-mTORC1 Axis: From Lysosomes to Stress Granules and Back

The tuberous sclerosis protein complex (TSC complex) is a key integrator of metabolic signals and cellular stress. In response to nutrient shortage and stresses, the TSC complex inhibits the mechanistic target of rapamycin complex 1 (mTORC1) at the lysosomes. mTORC1 is also inhibited by stress granu...

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Detalles Bibliográficos
Autores principales: Rehbein, Ulrike, Prentzell, Mirja Tamara, Cadena Sandoval, Marti, Heberle, Alexander Martin, Henske, Elizabeth P., Opitz, Christiane A., Thedieck, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586448/
https://www.ncbi.nlm.nih.gov/pubmed/34778262
http://dx.doi.org/10.3389/fcell.2021.751892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586448/
https://www.ncbi.nlm.nih.gov/pubmed/34778262
http://dx.doi.org/10.3389/fcell.2021.751892

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