Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity

We have structurally and functionally characterized Skl and Pal endolysins, the latter being the first endolysin shown to kill effectively Streptococcus pneumoniae, a leading cause of deathly diseases. We have proved that Skl and Pal are cysteine-amidases whose catalytic domains, from CHAP and Amida...

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Detalles Bibliográficos
Autores principales: Gallego-Páramo, Cristina, Hernández-Ortiz, Noelia, Buey, Rubén M., Rico-Lastres, Palma, García, Guadalupe, Díaz, J. Fernando, García, Pedro, Menéndez, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586454/
https://www.ncbi.nlm.nih.gov/pubmed/34777288
http://dx.doi.org/10.3389/fmicb.2021.740914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586454/
https://www.ncbi.nlm.nih.gov/pubmed/34777288
http://dx.doi.org/10.3389/fmicb.2021.740914

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