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Resetting amino acid metabolism of cancer cells by ATB(0,+)-targeted nanoparticles for enhanced anticancer therapy

Reprogramed cellular metabolism is one of the most significant hallmarks of cancer. All cancer cells exhibit increased demand for specific amino acids, and become dependent on either an exogenous supply or upregulated de novo synthesis. The resultant enhanced availability of amino acids supports the...

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Detalles Bibliográficos
Autores principales: Kou, Longfa, Jiang, Xinyu, Tang, Yingying, Xia, Xing, Li, Yingtao, Cai, Aimin, Zheng, Hailun, Zhang, Hailin, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586589/
https://www.ncbi.nlm.nih.gov/pubmed/34820552
http://dx.doi.org/10.1016/j.bioactmat.2021.07.009