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Resetting amino acid metabolism of cancer cells by ATB(0,+)-targeted nanoparticles for enhanced anticancer therapy
Reprogramed cellular metabolism is one of the most significant hallmarks of cancer. All cancer cells exhibit increased demand for specific amino acids, and become dependent on either an exogenous supply or upregulated de novo synthesis. The resultant enhanced availability of amino acids supports the...
Autores principales: | Kou, Longfa, Jiang, Xinyu, Tang, Yingying, Xia, Xing, Li, Yingtao, Cai, Aimin, Zheng, Hailun, Zhang, Hailin, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586589/ https://www.ncbi.nlm.nih.gov/pubmed/34820552 http://dx.doi.org/10.1016/j.bioactmat.2021.07.009 |
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