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MK‐6, a novel not‐α IL‐2, elicits a potent antitumor activity by improving the effector to regulatory T cell balance

IL‐2 is a pleiotropic cytokine that regulates immune cell homeostasis. Its immunomodulatory function has been used clinically as an active immunotherapy agent for metastatic cancers. However, severe adverse effects, including the vascular leak syndrome and the preferential stimulation of anti‐immuno...

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Detalles Bibliográficos
Autores principales: Kobayashi, Maki, Kojima, Katsuhiko, Murayama, Kazutaka, Amano, Yuji, Koyama, Takashi, Ogama, Naoko, Takeshita, Toshikazu, Fukuhara, Tatsuro, Tanaka, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586658/
https://www.ncbi.nlm.nih.gov/pubmed/34545658
http://dx.doi.org/10.1111/cas.15127