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MK‐6, a novel not‐α IL‐2, elicits a potent antitumor activity by improving the effector to regulatory T cell balance
IL‐2 is a pleiotropic cytokine that regulates immune cell homeostasis. Its immunomodulatory function has been used clinically as an active immunotherapy agent for metastatic cancers. However, severe adverse effects, including the vascular leak syndrome and the preferential stimulation of anti‐immuno...
Autores principales: | Kobayashi, Maki, Kojima, Katsuhiko, Murayama, Kazutaka, Amano, Yuji, Koyama, Takashi, Ogama, Naoko, Takeshita, Toshikazu, Fukuhara, Tatsuro, Tanaka, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586658/ https://www.ncbi.nlm.nih.gov/pubmed/34545658 http://dx.doi.org/10.1111/cas.15127 |
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