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DOC‐2/DAB2 interactive protein destabilizes c‐Myc to impair the growth and self‐renewal of colon tumor‐repopulating cells

Colorectal carcinoma (CRC) remains a huge challenge in clinical treatment due to tumor metastasis and recurrence. Stem cell‐like colon tumor‐repopulating cells (TRCs) are a subpopulation of cancer cells with highly tumorigenic and chemotherapy resistant properties. The core transcription factor c‐My...

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Detalles Bibliográficos
Autores principales: Li, Haiou, Zhou, Yunjiao, Wang, Meng, Wang, Haizhou, Zhang, Yangyang, Peng, Ruyi, Zhang, Ruike, Zhang, Meng, Zhang, Mengna, Qiu, Peishan, Liu, Lan, Zhao, Qiu, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586666/
https://www.ncbi.nlm.nih.gov/pubmed/34449943
http://dx.doi.org/10.1111/cas.15120