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C644‐0303, a small‐molecule inhibitor of the Wnt/β‐catenin pathway, suppresses colorectal cancer growth

The Wnt/β‐catenin signaling pathway plays an important role in tissue homeostasis, and its malignant activation is closely related to the occurrence and development of many cancers, especially colorectal cancer with adenomatous polyposis coli (APC) and CTNNB1 mutations. By applying a TCF/lymphoid‐en...

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Detalles Bibliográficos
Autores principales: Yan, Yu, Zhang, Yidan, Li, Mengyuan, Zhang, Yazhuo, Zhang, Xinxin, Zhang, Xiaonan, Xu, Yuting, Wei, Wei, Wang, Jie, Xu, Xiaohan, Song, Qiaoling, Zhao, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586673/
https://www.ncbi.nlm.nih.gov/pubmed/34431598
http://dx.doi.org/10.1111/cas.15118