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Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers

Screening custom‐made libraries of inhibitors may reveal novel drugs for treating pancreatic cancer. In this manner, we identified ispinesib as a candidate and attempted to determine its clinical efficacy and the biological significance of its functional target Eg5 in pancreatic cancer. One hundred...

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Detalles Bibliográficos
Autores principales: Murase, Yoshiki, Ono, Hiroaki, Ogawa, Kosuke, Yoshioka, Risa, Ishikawa, Yoshiya, Ueda, Hiroki, Akahoshi, Keiichi, Ban, Daisuke, Kudo, Atsushi, Tanaka, Shinji, Tanabe, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586681/
https://www.ncbi.nlm.nih.gov/pubmed/34510663
http://dx.doi.org/10.1111/cas.15134