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Comparing the Effect of Piperine and Ilepcimide on the Pharmacokinetics of Curcumin in SD Rats

The poor bioavailability and rapid metabolism of curcumin (CUR) restrict its clinical application. Piperine (PIP), which was extracted from natural compounds, can increase the plasma concentration of curcumin in humanidad. As an artificial synthetic piperine analog, silepcimide (ILE) has significant...

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Detalles Bibliográficos
Autores principales: Wang, Peijian, Li, Hui, Lin, Zhexuan, Luo, Hongjun, Luo, Wenhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586700/
https://www.ncbi.nlm.nih.gov/pubmed/34776952
http://dx.doi.org/10.3389/fphar.2021.725362