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Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium

Oral insulin delivery could change the life of millions of diabetic patients as an effective, safe, easy-to-use, and affordable alternative to insulin injections, known by an inherently thwarted patient compliance. Here, we designed a multistage nanoparticle (NP) system capable of circumventing the...

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Detalles Bibliográficos
Autores principales: Martins, João P., Figueiredo, Patrícia, Wang, Shiqi, Espo, Erika, Celi, Elena, Martins, Beatriz, Kemell, Marianna, Moslova, Karina, Mäkilä, Ermei, Salonen, Jarno, Kostiainen, Mauri A., Celia, Christian, Cerullo, Vincenzo, Viitala, Tapani, Sarmento, Bruno, Hirvonen, Jouni, Santos, Hélder A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586719/
https://www.ncbi.nlm.nih.gov/pubmed/34820572
http://dx.doi.org/10.1016/j.bioactmat.2021.08.007