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Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium

Oral insulin delivery could change the life of millions of diabetic patients as an effective, safe, easy-to-use, and affordable alternative to insulin injections, known by an inherently thwarted patient compliance. Here, we designed a multistage nanoparticle (NP) system capable of circumventing the...

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Bibliografiska uppgifter
Huvudupphovsmän: Martins, João P., Figueiredo, Patrícia, Wang, Shiqi, Espo, Erika, Celi, Elena, Martins, Beatriz, Kemell, Marianna, Moslova, Karina, Mäkilä, Ermei, Salonen, Jarno, Kostiainen, Mauri A., Celia, Christian, Cerullo, Vincenzo, Viitala, Tapani, Sarmento, Bruno, Hirvonen, Jouni, Santos, Hélder A.
Materialtyp: Online Artikel Text
Språk:English
Publicerad: KeAi Publishing 2021
Ämnen:
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586719/
https://www.ncbi.nlm.nih.gov/pubmed/34820572
http://dx.doi.org/10.1016/j.bioactmat.2021.08.007