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Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium
Oral insulin delivery could change the life of millions of diabetic patients as an effective, safe, easy-to-use, and affordable alternative to insulin injections, known by an inherently thwarted patient compliance. Here, we designed a multistage nanoparticle (NP) system capable of circumventing the...
Autores principales: | Martins, João P., Figueiredo, Patrícia, Wang, Shiqi, Espo, Erika, Celi, Elena, Martins, Beatriz, Kemell, Marianna, Moslova, Karina, Mäkilä, Ermei, Salonen, Jarno, Kostiainen, Mauri A., Celia, Christian, Cerullo, Vincenzo, Viitala, Tapani, Sarmento, Bruno, Hirvonen, Jouni, Santos, Hélder A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586719/ https://www.ncbi.nlm.nih.gov/pubmed/34820572 http://dx.doi.org/10.1016/j.bioactmat.2021.08.007 |
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