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Mendelian randomisation highlights hypothyroidism as a causal determinant of idiopathic pulmonary fibrosis

BACKGROUND: Although the association between hypothyroidism and idiopathic pulmonary fibrosis (IPF) is found in observational studies, it remains uncertain whether hypothyroidism causally influences IPF. METHODS: Two-sample Mendelian randomisation (MR) was conducted with hypothyroidism genome-wide a...

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Detalles Bibliográficos
Autores principales: Zhang, Yanan, Zhao, Meng, Guo, Ping, Wang, Yanjun, Liu, Lu, Zhao, Jinghua, Gao, Ling, Yuan, Zhongshang, Xue, Fuzhong, Zhao, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586742/
https://www.ncbi.nlm.nih.gov/pubmed/34749302
http://dx.doi.org/10.1016/j.ebiom.2021.103669