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Continued Androgen Signalling Inhibition improves Cabazitaxel Efficacy in Prostate Cancer

BACKGROUND: : The androgen receptor (AR) pathway is a key driver of neoplastic behaviour in the different stages of metastatic prostate cancer (mPCa). Targeting the AR therefore remains the cornerstone for mPCa treatment. We have previously reported that activation of AR signalling affects taxane ch...

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Detalles Bibliográficos
Autores principales: Mout, Lisanne, van Royen, Martin E., de Ridder, Corrina, Stuurman, Debra, van de Geer, Wesley S., Marques, Rute, Buck, Stefan A.J., French, Pim J., van de Werken, Harmen J.G., Mathijssen, Ron H.J., de Wit, Ronald, Lolkema, Martijn P., van Weerden, Wytske M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586743/
https://www.ncbi.nlm.nih.gov/pubmed/34749299
http://dx.doi.org/10.1016/j.ebiom.2021.103681