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Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity

The gut microbiome has emerged as a key regulator of obesity; however, its role in brown adipose tissue (BAT) metabolism and association with obesity remain to be elucidated. We found that the levels of circulating branched-chain amino acids (BCAA) and their cognate α-ketoacids (BCKA) were significa...

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Detalles Bibliográficos
Autores principales: Yoshida, Naofumi, Yamashita, Tomoya, Osone, Tatsunori, Hosooka, Tetsuya, Shinohara, Masakazu, Kitahama, Seiichi, Sasaki, Kengo, Sasaki, Daisuke, Yoneshiro, Takeshi, Suzuki, Tomohiro, Emoto, Takuo, Saito, Yoshihiro, Ozawa, Genki, Hirota, Yushi, Kitaura, Yasuyuki, Shimomura, Yoshiharu, Okamatsu-Ogura, Yuko, Saito, Masayuki, Kondo, Akihiko, Kajimura, Shingo, Inagaki, Takeshi, Ogawa, Wataru, Yamada, Takuji, Hirata, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586802/
https://www.ncbi.nlm.nih.gov/pubmed/34805797
http://dx.doi.org/10.1016/j.isci.2021.103342