Runx2 is required for hypertrophic chondrocyte mediated degradation of cartilage matrix during endochondral ossification

The RUNX2 transcription factor is a key regulator for the development of cartilage and bone. Global or resting chondrocyte-specific deletion of the Runx2 gene results in failure of chondrocyte hypertrophy, endochondral ossification, and perinatal lethality. The terminally mature hypertrophic chondro...

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Detalles Bibliográficos
Autores principales: Rashid, Harunur, Chen, Haiyan, Javed, Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586806/
https://www.ncbi.nlm.nih.gov/pubmed/34805821
http://dx.doi.org/10.1016/j.mbplus.2021.100088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586806/
https://www.ncbi.nlm.nih.gov/pubmed/34805821
http://dx.doi.org/10.1016/j.mbplus.2021.100088

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