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Runx2 is required for hypertrophic chondrocyte mediated degradation of cartilage matrix during endochondral ossification
The RUNX2 transcription factor is a key regulator for the development of cartilage and bone. Global or resting chondrocyte-specific deletion of the Runx2 gene results in failure of chondrocyte hypertrophy, endochondral ossification, and perinatal lethality. The terminally mature hypertrophic chondro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586806/ https://www.ncbi.nlm.nih.gov/pubmed/34805821 http://dx.doi.org/10.1016/j.mbplus.2021.100088 |