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Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages
A quarter of all seasonal influenza cases are caused by type B influenza virus (IBV) that also dominates periodically. Here, we investigated a recombinant adenovirus vaccine carrying a synthetic HA2 representing the consensus sequence of all IBV hemagglutinins. The vaccine fully protected mice from...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586812/ https://www.ncbi.nlm.nih.gov/pubmed/34805790 http://dx.doi.org/10.1016/j.isci.2021.103328 |