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T-cell dysfunction in chronic lymphocytic leukemia from an epigenetic perspective

Cellular immunotherapeutic approaches such as chimeric antigen receptor (CAR) T-cell therapy in chronic lymphocytic leukemia (CLL) thus far have not met the high expectations. Therefore it is essential to better understand the molecular mechanisms of CLLinduced T-cell dysfunction. Even though a sign...

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Detalles Bibliográficos
Autores principales: Peters, Fleur S., Strefford, Jonathan C., Eldering, Eric, Kater, Arnon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586819/
https://www.ncbi.nlm.nih.gov/pubmed/33691381
http://dx.doi.org/10.3324/haematol.2020.267914