Organotypic spinal cord cultures: An in vitro 3D model to preliminary screen treatments for spinal muscular atrophy

Spinal muscular atrophy (SMA) is a severe neuromuscular disease affecting children, due to mutation/deletion of survival motor neuron 1 (SMN1) gene. The lack of functional protein SMN determines motor neuron (MN) degeneration and skeletal muscle atrophy, leading to premature death due to respiratory...

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Detalles Bibliográficos
Autores principales: Boido, Marina, De Amicis, Elena, Mareschi, Katia, Fagioli, Franca, Vercelli, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586821/
https://www.ncbi.nlm.nih.gov/pubmed/34734684
http://dx.doi.org/10.4081/ejh.2021.3294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586821/
https://www.ncbi.nlm.nih.gov/pubmed/34734684
http://dx.doi.org/10.4081/ejh.2021.3294

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