RNA Activation—A Novel Approach to Therapeutically Upregulate Gene Transcription

RNA activation (RNAa) is a mechanism whereby RNA oligos complementary to genomic sequences around the promoter region of genes increase the transcription output of their target gene. Small activating RNA (saRNA) mediate RNAa through interaction with protein co-factors to facilitate RNA polymerase II...

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Detalles Bibliográficos
Autores principales: Tan, Choon Ping, Sinigaglia, Laura, Gomez, Valentí, Nicholls, Joanna, Habib, Nagy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586927/
https://www.ncbi.nlm.nih.gov/pubmed/34770939
http://dx.doi.org/10.3390/molecules26216530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586927/
https://www.ncbi.nlm.nih.gov/pubmed/34770939
http://dx.doi.org/10.3390/molecules26216530

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