Pan-ROCK and ROCK2 Inhibitors Affect Dexamethasone-Treated 2D- and 3D-Cultured Human Trabecular Meshwork (HTM) Cells in Opposite Manners

Effects of a pan-ROCK-inhibitor, ripasudil (Rip), and a ROCK2 inhibitor, KD025 on dexamethasone (DEX)-treated human trabecular meshwork (HTM) cells as a model of steroid-induced glaucoma were investigated. In the presence of Rip or KD025, DEX-treated HTM cells were subjected to permeability analysis...

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Detalles Bibliográficos
Autores principales: Watanabe, Megumi, Ida, Yosuke, Furuhashi, Masato, Tsugeno, Yuri, Hikage, Fumihito, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587022/
https://www.ncbi.nlm.nih.gov/pubmed/34770791
http://dx.doi.org/10.3390/molecules26216382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587022/
https://www.ncbi.nlm.nih.gov/pubmed/34770791
http://dx.doi.org/10.3390/molecules26216382

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