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Synthesis and Biological Evaluation of Harmirins, Novel Harmine–Coumarin Hybrids as Potential Anticancer Agents

As cancer remains one of the major health burdens worldwide, novel agents, due to the development of resistance, are needed. In this work, we designed and synthesized harmirins, which are hybrid compounds comprising harmine and coumarin scaffolds, evaluated their antiproliferative activity, and cond...

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Detalles Bibliográficos
Autores principales: Pavić, Kristina, Beus, Maja, Poje, Goran, Uzelac, Lidija, Kralj, Marijeta, Rajić, Zrinka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587047/
https://www.ncbi.nlm.nih.gov/pubmed/34770906
http://dx.doi.org/10.3390/molecules26216490