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Utilization of Sodium Nitroprusside as an Intestinal Permeation Enhancer for Lipophilic Drug Absorption Improvement in the Rat Proximal Intestine

As advanced synthetic technology has enabled drug candidate development with complex structure, resulting in low solubility and membrane permeability, the strategies to improve poorly absorbed drug bioavailability have attracted the attention of pharmaceutical companies. It has been demonstrated tha...

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Detalles Bibliográficos
Autores principales: Kishimoto, Hisanao, Miyazaki, Kaori, Tedzuka, Hiroshi, Ozawa, Ryosuke, Kobayashi, Hanai, Shirasaka, Yoshiyuki, Inoue, Katsuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587071/
https://www.ncbi.nlm.nih.gov/pubmed/34770805
http://dx.doi.org/10.3390/molecules26216396