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Deep Membrane Proteome Profiling Reveals Overexpression of Prostate-Specific Membrane Antigen (PSMA) in High-Risk Human Paraganglioma and Pheochromocytoma, Suggesting New Theranostic Opportunity

Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors arising from chromaffin cells of adrenal medulla or sympathetic or parasympathetic paraganglia, respectively. To identify new therapeutic targets, we performed a detailed membrane-focused proteomic analysis of five human par...

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Detalles Bibliográficos
Autores principales: Vit, Ondrej, Patel, Mayank, Musil, Zdenek, Hartmann, Igor, Frysak, Zdenek, Miettinen, Markku, Pacak, Karel, Petrak, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587166/
https://www.ncbi.nlm.nih.gov/pubmed/34770976
http://dx.doi.org/10.3390/molecules26216567