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Aqueous Solutions of Peptides and Trialkylamines Lead to Unexpected Peptide Modification

When trialkylamines are added to buffered solutions of peptides, unexpected adducts can be formed. These adducts correspond to Schiff base products. The source of the reaction is the unexpected presence of aldehydes in amines. The aldehydes can be detected in a few ways. Most importantly, they can l...

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Detalles Bibliográficos
Autores principales: Ma, Yiran, Gandhi, Puja J., Reilly, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587169/
https://www.ncbi.nlm.nih.gov/pubmed/34770892
http://dx.doi.org/10.3390/molecules26216481