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Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2

BACKGROUND: In ginseng, there exists a glycolipoprotein complex with a special form of lipid LPAs called Gintonin. The purpose of this study is to show that Gintonin has a therapeutic effect on rheumatoid arthritis through LPA2 receptors. METHODS: Fibroblast-like synoviocytes (FLS) were treated with...

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Detalles Bibliográficos
Autores principales: Kim, Mijin, Sur, Bongjun, Villa, Thea, Yun, Jaesuk, Nah, Seung Yeol, Oh, Seikwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587511/
https://www.ncbi.nlm.nih.gov/pubmed/34803427
http://dx.doi.org/10.1016/j.jgr.2021.02.001