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The Involvement of PDE4 in the Protective Effects of Melatonin on Cigarette-Smoke-Induced Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a significant disease threatening human health. Currently, roflumilast, a phosphodiesterase (PDE)4 inhibitor, is recommended as a therapeutic agent for COPD. In this study, we investigated the therapeutic effects of melatonin against COPD, focusing on...

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Detalles Bibliográficos
Autores principales: Lim, Je-Oh, Kim, Woong-Il, Lee, Se-Jin, Pak, So-Won, Cho, Young-Kwon, Kim, Jong-Choon, Kim, Joong-Sun, Shin, In-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587536/
https://www.ncbi.nlm.nih.gov/pubmed/34771000
http://dx.doi.org/10.3390/molecules26216588