Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT

The permeability transition (PT) is an increased permeation of the inner mitochondrial membrane due to the opening of the PT pore (PTP), a Ca(2+)-activated high conductance channel involved in Ca(2+) homeostasis and cell death. Alterations of the PTP have been associated with many pathological condi...

Descripción completa

Detalles Bibliográficos
Autores principales: Carrer, Andrea, Laquatra, Claudio, Tommasin, Ludovica, Carraro, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587538/
https://www.ncbi.nlm.nih.gov/pubmed/34770872
http://dx.doi.org/10.3390/molecules26216463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587538/
https://www.ncbi.nlm.nih.gov/pubmed/34770872
http://dx.doi.org/10.3390/molecules26216463

Ejemplares similares