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Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT
The permeability transition (PT) is an increased permeation of the inner mitochondrial membrane due to the opening of the PT pore (PTP), a Ca(2+)-activated high conductance channel involved in Ca(2+) homeostasis and cell death. Alterations of the PTP have been associated with many pathological condi...
Autores principales: | Carrer, Andrea, Laquatra, Claudio, Tommasin, Ludovica, Carraro, Michela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587538/ https://www.ncbi.nlm.nih.gov/pubmed/34770872 http://dx.doi.org/10.3390/molecules26216463 |
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