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Identification of Novel Antagonists Targeting Cannabinoid Receptor 2 Using a Multi-Step Virtual Screening Strategy

The endocannabinoid system plays an essential role in the regulation of analgesia and human immunity, and Cannabinoid Receptor 2 (CB2) has been proved to be an ideal target for the treatment of liver diseases and some cancers. In this study, we identified CB2 antagonists using a three-step “deep lea...

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Detalles Bibliográficos
Autores principales: Wang, Mukuo, Hou, Shujing, Liu, Ye, Li, Dongmei, Lin, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587544/
https://www.ncbi.nlm.nih.gov/pubmed/34771087
http://dx.doi.org/10.3390/molecules26216679