Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer’s Disease‒Synthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide. The limited pharmacological approaches based on cholinesterase inhibitors only provide symptomatic relief to AD patients. Moreover, the adverse side effects such as nausea, vomiting, los...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaib, Sumera, Munir, Rubina, Younas, Muhammad Tayyab, Kausar, Naghmana, Ibrar, Aliya, Aqsa, Sehar, Shahid, Noorma, Asif, Tahira Tasneem, Alsaab, Hashem O., Khan, Imtiaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587653/
https://www.ncbi.nlm.nih.gov/pubmed/34770983
http://dx.doi.org/10.3390/molecules26216573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587653/
https://www.ncbi.nlm.nih.gov/pubmed/34770983
http://dx.doi.org/10.3390/molecules26216573

Ejemplares similares