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Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer’s Disease‒Synthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide. The limited pharmacological approaches based on cholinesterase inhibitors only provide symptomatic relief to AD patients. Moreover, the adverse side effects such as nausea, vomiting, los...
Autores principales: | Zaib, Sumera, Munir, Rubina, Younas, Muhammad Tayyab, Kausar, Naghmana, Ibrar, Aliya, Aqsa, Sehar, Shahid, Noorma, Asif, Tahira Tasneem, Alsaab, Hashem O., Khan, Imtiaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587653/ https://www.ncbi.nlm.nih.gov/pubmed/34770983 http://dx.doi.org/10.3390/molecules26216573 |
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