Mouse Acidic Chitinase Effectively Degrades Random-Type Chitosan to Chitooligosaccharides of Variable Lengths under Stomach and Lung Tissue pH Conditions

Chitooligosaccharides exhibit several biomedical activities, such as inflammation and tumorigenesis reduction in mammals. The mechanism of the chitooligosaccharides’ formation in vivo has been, however, poorly understood. Here we report that mouse acidic chitinase (Chia), which is widely expressed i...

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Detalles Bibliográficos
Autores principales: Wakita, Satoshi, Sugahara, Yasusato, Nakamura, Masayuki, Kobayashi, Syunsuke, Matsuda, Kazuhisa, Takasaki, Chinatsu, Kimura, Masahiro, Kida, Yuta, Uehara, Maiko, Tabata, Eri, Hiraoka, Koji, Seki, Shiro, Matoska, Vaclav, Bauer, Peter O., Oyama, Fumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587675/
https://www.ncbi.nlm.nih.gov/pubmed/34771117
http://dx.doi.org/10.3390/molecules26216706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587675/
https://www.ncbi.nlm.nih.gov/pubmed/34771117
http://dx.doi.org/10.3390/molecules26216706

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