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Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

The delta opioid receptor (DOR) is a crucial receptor system that regulates pain, mood, anxiety, and similar mental states. DOR agonists, such as SNC80, and DOR-neutral antagonists, such as naltrindole, were developed to investigate the DOR in vivo and as potential therapeutics for pain and depressi...

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Detalles Bibliográficos
Autores principales: Tanguturi, Parthasaradhireddy, Pathak, Vibha, Zhang, Sixue, Moukha-Chafiq, Omar, Augelli-Szafran, Corinne E., Streicher, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587863/
https://www.ncbi.nlm.nih.gov/pubmed/34771099
http://dx.doi.org/10.3390/molecules26216693