Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE(2) Productions and Nitric Oxide in Murine RAW 264.7 Macrophages

A series of thirteen triarylpyrazole analogs were investigated as inhibitors of lipopolysaccharide (LPS)-induced prostaglandin E(2) (PGE(2)) and nitric oxide (NO) production in RAW 264.7 macrophages. The target compounds 1a–m have first been assessed for cytotoxicity against RAW 264.7 macrophages to...

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Detalles Bibliográficos
Autores principales: Gamal El-Din, Mahmoud M., El-Gamal, Mohammed I., Kwon, Young-Do, Kim, Su-Yeon, Han, Hee-Soo, Park, Sang-Eun, Oh, Chang-Hyun, Lee, Kyung-Tae, Kim, Hee-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587869/
https://www.ncbi.nlm.nih.gov/pubmed/34770896
http://dx.doi.org/10.3390/molecules26216489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587869/
https://www.ncbi.nlm.nih.gov/pubmed/34770896
http://dx.doi.org/10.3390/molecules26216489

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