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Three-Dimensional Single Molecule Localization Microscopy Reveals the Topography of the Immunological Synapse at Isotropic Precision below 15 nm

[Image: see text] T-cells engage with antigen-presenting cells in search for antigenic peptides and form transient interfaces termed immunological synapses. Synapse topography affects receptor binding rates and the mutual segregation of proteins due to size exclusion effects. It is hence important t...

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Detalles Bibliográficos
Autores principales: Velas, Lukas, Brameshuber, Mario, Huppa, Johannes B., Kurz, Elke, Dustin, Michael L., Zelger, Philipp, Jesacher, Alexander, Schütz, Gerhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587899/
https://www.ncbi.nlm.nih.gov/pubmed/34709845
http://dx.doi.org/10.1021/acs.nanolett.1c03160