Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate

In the current work, mesoporous magnesium carbonate (MMC) was used to suppress crystallization of the poorly soluble drug celecoxib (CXB). This resulted in both a higher dissolution rate and supersaturation of the substance in vitro as well as an increased transfer of CXB over a Caco-2 cell membrane...

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Detalles Bibliográficos
Autores principales: Gómez de la Torre, Johan, Bergström, Christel, Zardán Gómez de la Torre, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588146/
https://www.ncbi.nlm.nih.gov/pubmed/34770762
http://dx.doi.org/10.3390/molecules26216353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588146/
https://www.ncbi.nlm.nih.gov/pubmed/34770762
http://dx.doi.org/10.3390/molecules26216353

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