Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

In the current study, eight new hybrids of the NSAIDs, ibuprofen and ketoprofen with five pyrrolizine/indolizine derivatives were designed and synthesized. The chemical structures of these hybrids were confirmed by spectral and elemental analyses. The antiproliferative activities of these hybrids (5...

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Detalles Bibliográficos
Autores principales: Abourehab, Mohammed A. S., Alqahtani, Alaa M., Almalki, Faisal A., Zaher, Dana M., Abdalla, Ashraf N., Gouda, Ahmed M., Beshr, Eman A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588198/
https://www.ncbi.nlm.nih.gov/pubmed/34770990
http://dx.doi.org/10.3390/molecules26216582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588198/
https://www.ncbi.nlm.nih.gov/pubmed/34770990
http://dx.doi.org/10.3390/molecules26216582

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