Development of Natural Polysaccharide–Based Nanoparticles of Berberine to Enhance Oral Bioavailability: Formulation, Optimization, Ex Vivo, and In Vivo Assessment

The phytogenous alkaloid berberine (BBR) has become a potential drug for the treatment of diabetes, hyperlipidemia, and cancer. However, its therapeutic potential is limited because ofpoor intestinal absorption due to its efflux by the P-gp expressed in the intestinal lumen. Therefore, we aimed to d...

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Detalles Bibliográficos
Autores principales: Kohli, Kanchan, Mujtaba, Ali, Malik, Rozina, Amin, Saima, Alam, Md Sarfaraz, Ali, Abuzer, Barkat, Md. Abul, Ansari, Mohammad Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588213/
https://www.ncbi.nlm.nih.gov/pubmed/34771389
http://dx.doi.org/10.3390/polym13213833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588213/
https://www.ncbi.nlm.nih.gov/pubmed/34771389
http://dx.doi.org/10.3390/polym13213833

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