Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods

Streptomyces are well-known producers of a range of different secondary metabolites, including antibiotics and other bioactive compounds. Recently, it has been demonstrated that “silent” biosynthetic gene clusters (BGCs) can be activated by heterologously expressing transcriptional regulators from o...

Descripción completa

Detalles Bibliográficos
Autores principales: Beck, Charlotte, Gren, Tetiana, Ortiz-López, Francisco Javier, Jørgensen, Tue Sparholt, Carretero-Molina, Daniel, Martín Serrano, Jesús, Tormo, José R., Oves-Costales, Daniel, Kontou, Eftychia E., Mohite, Omkar S., Mingyar, Erik, Stegmann, Evi, Genilloud, Olga, Weber, Tilmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588249/
https://www.ncbi.nlm.nih.gov/pubmed/34770989
http://dx.doi.org/10.3390/molecules26216580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588249/
https://www.ncbi.nlm.nih.gov/pubmed/34770989
http://dx.doi.org/10.3390/molecules26216580

Ejemplares similares