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Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells

Background: The aim of the study was to examine the molecular mechanism of the anticancer action of a monoclonal antibody against MUC1 and a diisoquinoline derivative (OM-86II) in human gastric cancer cells. Methods: The cell viability was measured by the MTT assay. The disruption of mitochondrial m...

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Detalles Bibliográficos
Autores principales: Gornowicz, Agnieszka, Szymanowski, Wojciech, Bielawski, Krzysztof, Kałuża, Zbigniew, Michalak, Olga, Bielawska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588261/
https://www.ncbi.nlm.nih.gov/pubmed/34770912
http://dx.doi.org/10.3390/molecules26216504